Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10606364 | 0.87 | KCNN4 (0.50) | KCNN4CES2CES1KIF11NPC1 | |
| SCHEMBL461095 | 0.84 | KCNN4 (0.48) | KCNN4MAPTNPSR1ALDH1A1KMT2A | |
| SCHEMBL6045338 | 0.82 | KCNN4 (0.55) | KCNN4CES2CES1KIF11NPC1 | |
| SCHEMBL2316036 | 0.81 | KCNN4 (0.53) | KCNN4CES2CES1KIF11NPC1 | |
| SCHEMBL17080312 | 0.78 | CES1 (0.58) | KCNN4CES2CES1KIF11NPC1 | |
| SCHEMBL1507665 | 0.76 | CA1 (0.54) | CES2CES1NPC1RAB9AMAPT | |
| SCHEMBL30241792 | 0.75 | KCNN4 (0.56) | KCNN4CES2CES1KIF11NPC1 | |
| SCHEMBL30241803 | 0.75 | KIF11 (0.53) | KCNN4CES2CES1KIF11NPC1 | |
| SCHEMBL5192276 | 0.75 | KCNN4 (0.60) | KCNN4CES2CES1MAPTNPSR1 | |
| SCHEMBL5838974 | 0.74 | ALDH1A1 (0.41) | KCNN4CES2CES1KIF11NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0204444-B1 | BINDER FOR ANTI-FOULING PAINTS | COURTAULDS COATINGS (HOLDINGS) LIMITED (GB) | 1989-08-02 | — | — | EP | claimed |