Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 2/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.42 |
| ▸ | FEN1 | P39748 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11298443 | 0.87 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10CACNA1B | |
| SCHEMBL8848783 | 0.87 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10CACNA1B | |
| SCHEMBL30889519 | 0.85 | ALDH1A1 (0.60) | KDM4EALDH1A1HPGDHSD17B10CACNA1B | |
| SCHEMBL2228176 | 0.85 | ALDH1A1 (0.60) | KDM4EALDH1A1HPGDHSD17B10CACNA1B | |
| SCHEMBL30519265 | 0.84 | DDR1 (0.46) | KDM4EALDH1A1HPGDHSD17B10CFTR | |
| Hydrochloric Acid SCHEMBL8492943 | 0.84 | ALDH1A1 (0.58) | KDM4EALDH1A1HPGDHSD17B10CACNA1B | |
| SCHEMBL31374385 | 0.84 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDHSD17B10CACNA1B | |
| SCHEMBL8182991 | 0.84 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDHSD17B10CACNA1B | |
| Formaldehyde SCHEMBL28289725 | 0.83 | ALDH1A1 (0.57) | KDM4EALDH1A1HPGDHSD17B10CACNA1B | |
| SCHEMBL29123913 | 0.81 | CFTR (0.61) | KDM4EALDH1A1HPGDHSD17B10CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018162329-A1 | HPPD VARIANTS AND METHODS OF USE | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-09-13 | — | — | WO | claimed |
| CN-108349916-A | The thermodynamically stable crystalline modifications of 2- methyl-N- (5- methyl-1s, 3,4- oxadiazole -2- bases) -3- (methyl sulphonyl) -4- (trifluoromethyl) benzamide | 拜耳作物科学股份公司 | 2018-07-31 | — | — | CN | claimed |
| EP-3117003-A2 | HPPD VARIANTS AND METHODS OF USE | Bayer Cropscience LP (US) | 2017-01-18 | — | — | EP | claimed |
| WO-2015138394-A2 | HPPD VARIANTS AND METHODS OF USE | BAYER CROPSCIENCE LP (US) | 2015-09-17 | — | — | WO | claimed |
| CN-119977852-A | Synthesis method of 2-methylsulfonyl-4-trifluoromethyl benzoic acid | 山东极地医药科技有限公司 | 2025-05-13 | — | — | CN | disclosed |
| CN-109705005-B | 2-methylsulfonyl-4-trifluoromethylbenzoic acid derivative and preparation method and application thereof | 帕潘纳(北京)科技有限公司 | 2020-12-11 | — | — | CN | disclosed |
| CN-109705005-A | A kind of 2- methylsulfonyl -4- trifluoromethylbenzoic acid derivative and preparation method and application | 帕潘纳(北京)科技有限公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-107406395-A | The salt of N (base of 1,3,4 oxadiazole 2) aryl carboxylic acid amides and its purposes as herbicide | 拜耳作物科学股份公司 | 2017-11-28 | — | — | CN | disclosed |
| CN-107075488-A | Hppd variants and methods of use | 拜耳作物科学股份公司 | 2017-08-18 | — | — | CN | disclosed |