SCHEMBL2228176

SCHEMBL2228176

CS(=O)(=O)c1cc(C(F)(F)F)ccc1C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.60
HPGD P15428 3/20 0.60
KDM4E B2RXH2 2/20 0.60
HSD17B10 Q99714 2/20 0.60
USP2 O75604 1/20 0.53
CYP2C19 P33261 1/20 0.53
ACLY P53396 1/20 0.47
CACNA1B Q00975 2/20 0.46
NR1I2 O75469 1/20 0.46
CES2 O00748 2/20 0.46
RXRA P19793 1/20 0.45
RXRB P28702 1/20 0.45
SORT1 Q99523 4/20 0.45
KDM1A O60341 2/20 0.45
TAS2R14 Q9NYV8 1/20 0.43
CFTR P13569 1/20 0.43
ABCB11 O95342 1/20 0.43
GRIK1 P39086 1/20 0.43
MEN1 O00255 1/20 0.42
CYP1A2 P05177 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30889519 1.00 ALDH1A1 (0.60) ALDH1A1HPGDKDM4EHSD17B10USP2
Hydrochloric Acid SCHEMBL8492943 0.98 ALDH1A1 (0.58) ALDH1A1HPGDKDM4EHSD17B10USP2
Formaldehyde SCHEMBL28289725 0.97 ALDH1A1 (0.57) ALDH1A1HPGDKDM4EHSD17B10USP2
SCHEMBL8848783 0.88 KDM4E (0.49) ALDH1A1HPGDKDM4EHSD17B10USP2
SCHEMBL29033911 0.87 ALDH1A1 (0.45) ALDH1A1HPGDKDM4EHSD17B10USP2
SCHEMBL5356923 0.87 ALDH1A1 (0.45) ALDH1A1HPGDKDM4EHSD17B10USP2
SCHEMBL29243250 0.87 ALDH1A1 (0.56) ALDH1A1HPGDKDM4EHSD17B10USP2
SCHEMBL31374385 0.85 ALDH1A1 (0.46) ALDH1A1HPGDKDM4EHSD17B10USP2
SCHEMBL17080315 0.85 KDM4E (0.50) ALDH1A1HPGDKDM4EHSD17B10USP2
SCHEMBL8182991 0.85 ALDH1A1 (0.46) ALDH1A1HPGDKDM4EHSD17B10USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024116184-A1 PROCESS FOR THE PREPARATION OF 2-ALKYLSULFONYL SUBSTITUTED BENZOIC ACID DERIVATIVES ADAMA AGAN LTD. (IL) 2024-06-06 WO claimed
CN-112010793-B Synthetic method of 2-methylsulfonyl-4-trifluoromethylbenzoic acid 帕潘纳(北京)科技有限公司 2021-04-06 CN claimed
CN-109705005-B 2-methylsulfonyl-4-trifluoromethylbenzoic acid derivative and preparation method and application thereof 帕潘纳(北京)科技有限公司 2020-12-11 CN claimed
CN-112010793-A Synthetic method of 2-methylsulfonyl-4-trifluoromethylbenzoic acid 帕潘纳(北京)科技有限公司 2020-12-01 CN claimed
CN-109705005-A A kind of 2- methylsulfonyl -4- trifluoromethylbenzoic acid derivative and preparation method and application 帕潘纳(北京)科技有限公司 2019-05-03 CN claimed
US-12319663-B2 Alkene-containing amide compound and application thereof SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) 2025-06-03 US disclosed
CN-119192083-A Preparation method of sulfonylgrass pyrazole intermediate 山东潍坊润丰化工股份有限公司 2024-12-27 CN disclosed
CN-112204008-B Sulfonylaminobenzamides and sulfonylaminobenzamide derivatives 奥索生物公司 2024-07-05 CN disclosed
WO-2024116184-A1 PROCESS FOR THE PREPARATION OF 2-ALKYLSULFONYL SUBSTITUTED BENZOIC ACID DERIVATIVES ADAMA AGAN LTD. (IL) 2024-06-06 WO disclosed
WO-2024107778-A1 NOVEL PROTEASE INHIBITORS FOR TREATMENT OF CORONAVIRUS INFECTIONS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-05-23 WO disclosed
CN-112939953-B Benzamide compound and application thereof as herbicide 沈阳中化农药化工研发有限公司 2024-04-23 CN disclosed
CN-112624974-B Cinnamate compound and application thereof 沈阳中化农药化工研发有限公司 2024-01-30 CN disclosed
EP-0487357-B1 4 Benzoyl isoxazole derivatives RHONE POULENC AGRICULTURE (GB) 1997-07-02 EP disclosed
CN-1149050-A New compositions of matter RHONE POULENC AGRICULTURE (GB) 1997-05-07 CN disclosed
EP-0527036-B1 4-Benzoylisoxazole derivatives and their use as herbicides RHONE POULENC AGRICULTURE (GB) 1996-11-06 EP disclosed
EP-0496631-B1 2-Cyano-1,3-dione herbicides RHONE POULENC AGRICULTURE (GB) 1995-06-07 EP disclosed
EP-0527036-A1 4-Benzoylisoxazole derivatives and their use as herbicides RHONE-POULENC AGRICULTURE LTD. (GB) 1993-02-10 EP disclosed
CN-1063682-A Novel herbicide RHONE POULENC AGRICULTURE (GB) 1992-08-19 CN disclosed
EP-0496631-A1 2-Cyano-1,3-dione herbicides RHONE-POULENC AGRICULTURE LTD. (GB) 1992-07-29 EP disclosed
EP-0487357-A1 4 Benzoyl isoxazole derivatives RHONE-POULENC AGRICULTURE LTD. (GB) 1992-05-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12319663-B2 Alkene-containing amide compound and application thereof DDT, ASPH, ALK ALDH1A1 146/4885HPGD 2056/4885KDM4E 1393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.