Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGB | P11216 | 7/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.41 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.41 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.41 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17080323 | 1.00 | PYGB (0.44) | PYGBGAALGALS1LGALS3LGALS9 | |
| SCHEMBL20161660 | 1.00 | PYGB (0.44) | PYGBGAALGALS1LGALS3LGALS9 | |
| SCHEMBL20161682 | 1.00 | PYGB (0.44) | PYGBGAALGALS1LGALS3LGALS9 | |
| SCHEMBL28909060 | 1.00 | PYGB (0.44) | PYGBGAALGALS1LGALS3LGALS9 | |
| SCHEMBL20265963 | 1.00 | PYGB (0.44) | PYGBGAALGALS1LGALS3LGALS9 | |
| SCHEMBL20161685 | 1.00 | PYGB (0.44) | PYGBGAALGALS1LGALS3LGALS9 | |
| SCHEMBL20265967 | 1.00 | PYGB (0.44) | PYGBGAALGALS1LGALS3LGALS9 | |
| SCHEMBL17080340 | 1.00 | PYGB (0.44) | PYGBGAALGALS1LGALS3LGALS9 | |
| SCHEMBL21342377 | 0.84 | LGALS3 (0.49) | LGALS1LGALS3LGALS9LGALS8 | |
| SCHEMBL20161936 | 0.84 | LGALS3 (0.49) | LGALS1LGALS3LGALS9LGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357301-A1 | HEXOSE DERIVATIVES, PREPARATION AND USES THEREOF | FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA (PT) | 2023-11-09 | — | — | US | disclosed |
| US-11708387-B2 | Hexose derivatives, preparation and uses thereof | FACULDADE DE CIÊNCIAS DA UNIVERSIDADE DE LISBOA (PT) | 2023-07-25 | — | — | US | disclosed |
| US-20180170955-A1 | HEXOSE DERIVATIVES, PREPARATION AND USES THEREOF | UNIVERSIDADE NOVA DE LISBOA (PT) | 2018-06-21 | — | — | US | disclosed |
| EP-3116886-A1 | HEXOSE DERIVATIVES, PREPARATION AND USES THEREOF | Faculdade De Ciências da Universidade de Lisboa (PT) | 2017-01-18 | — | — | EP | disclosed |
| WO-2015137838-A1 | HEXOSE DERIVATIVES, PREPARATION AND USES THEREOF | EXTREMOCHEM, LDA. (PT) | 2015-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180170955-A1 | HEXOSE DERIVATIVES, PREPARATION AND USES THEREOF | HK1, SLC5A1, HK2 | PYGB 1510/4885GAA 1568/4885LGALS1 792/4885 |
| US-20230357301-A1 | HEXOSE DERIVATIVES, PREPARATION AND USES THEREOF | HK1, SLC5A1, HK2 | PYGB 1510/4885GAA 1568/4885LGALS1 792/4885 |
| US-11708387-B2 | Hexose derivatives, preparation and uses thereof | HK1, SLC5A1, HK2 | PYGB 1510/4885GAA 1568/4885LGALS1 792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.