Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20962292 | 0.85 | EPHX1 (0.46) | HDAC4HDAC1EPHX1TSHREPHX2 | |
| SCHEMBL20962328 | 0.85 | EPHX1 (0.46) | HDAC4HDAC1EPHX1TSHREPHX2 | |
| SCHEMBL20962291 | 0.84 | EPHX1 (0.42) | EPHX1TSHREPHX2SMN1; SMN2MEN1 | |
| SCHEMBL21716644 | 0.84 | EPHX1 (0.39) | HDAC4HDAC1EPHX1TSHREPHX2 | |
| SCHEMBL25919981 | 0.82 | EPHX1 (0.41) | HDAC4HDAC1EPHX1TSHREPHX2 | |
| SCHEMBL22386550 | 0.81 | EPHX1 (0.41) | HDAC4HDAC1EPHX1TSHREPHX2 | |
| SCHEMBL807923 | 0.81 | EPHX1 (0.41) | HDAC4HDAC1EPHX1TSHREPHX2 | |
| SCHEMBL20026739 | 0.76 | EPHX1 (0.45) | HDAC4HDAC1EPHX1CA3CA5A | |
| SCHEMBL25920320 | 0.76 | EPHX1 (0.45) | HDAC4HDAC1EPHX1CA3CA5A | |
| SCHEMBL25825388 | 0.74 | EPHX1 (0.42) | HDAC4HDAC1EPHX1CA3CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9133276-B2 | Prodrugs comprising an exendin linker conjugate | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2015-09-15 | — | — | US | disclosed |