Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22386550 | 0.87 | EPHX1 (0.41) | EPHX1TSHREPHX2SMN1; SMN2PAOX | |
| SCHEMBL807923 | 0.87 | EPHX1 (0.41) | EPHX1TSHREPHX2SMN1; SMN2PAOX | |
| SCHEMBL20962292 | 0.85 | EPHX1 (0.46) | EPHX1TSHREPHX2SMN1; SMN2MEN1 | |
| SCHEMBL20962328 | 0.85 | EPHX1 (0.46) | EPHX1TSHREPHX2SMN1; SMN2MEN1 | |
| SCHEMBL20962291 | 0.84 | EPHX1 (0.42) | EPHX1TSHREPHX2SMN1; SMN2PAOX | |
| SCHEMBL21716644 | 0.84 | EPHX1 (0.39) | EPHX1TSHREPHX2SMN1; SMN2MEN1 | |
| SCHEMBL25919987 | 0.83 | MAPT (0.40) | EPHX1EPHX2MEN1KMT2AMAPK1 | |
| SCHEMBL25919983 | 0.82 | EPHX1 (0.36) | EPHX1EPHX2PAOXHDAC3HDAC4 | |
| SCHEMBL17080653 | 0.82 | HDAC4 (0.39) | EPHX1TSHREPHX2SMN1; SMN2MEN1 | |
| SCHEMBL22386546 | 0.76 | MAPT (0.39) | EPHX1MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230248836-A1 | Dosage Regimen for a Controlled-Release PTH Compound | ASCENDIS PHARMA BONE DISEASES A/S (DK) | 2023-08-10 | — | — | US | disclosed |
| US-20230218722-A1 | PTH Compounds with Low Peak-To-Trough Ratios | ASCENDIS PHARMA BONE DISEASES AS (DK) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230248836-A1 | Dosage Regimen for a Controlled-Release PTH Compound | PTH1R, CALCA, CALCR | EPHX1 2663/4885TSHR 270/4885EPHX2 2676/4885 |
| US-20230218722-A1 | PTH Compounds with Low Peak-To-Trough Ratios | PTH1R, PTMS, FGF23 | EPHX1 1814/4885TSHR 42/4885EPHX2 1511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.