Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20962328 | 0.87 | EPHX1 (0.46) | EPHX1TSHREPHX2SMN1; SMN2MEN1 | |
| SCHEMBL20962292 | 0.87 | EPHX1 (0.46) | EPHX1TSHREPHX2SMN1; SMN2MEN1 | |
| SCHEMBL20962291 | 0.86 | EPHX1 (0.42) | EPHX1TSHREPHX2SMN1; SMN2MEN1 | |
| SCHEMBL25919981 | 0.84 | EPHX1 (0.41) | EPHX1TSHREPHX2SMN1; SMN2MEN1 | |
| SCHEMBL17080653 | 0.84 | HDAC4 (0.39) | EPHX1TSHREPHX2SMN1; SMN2MEN1 | |
| SCHEMBL22386550 | 0.83 | EPHX1 (0.41) | EPHX1TSHREPHX2SMN1; SMN2MEN1 | |
| SCHEMBL807923 | 0.83 | EPHX1 (0.41) | EPHX1TSHREPHX2SMN1; SMN2MEN1 | |
| SCHEMBL25919987 | 0.74 | MAPT (0.40) | EPHX1EPHX2MEN1KMT2A | |
| SCHEMBL25919983 | 0.73 | EPHX1 (0.36) | EPHX1EPHX2HDAC3HDAC4HDAC1 | |
| SCHEMBL22386546 | 0.73 | MAPT (0.39) | EPHX1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200046725-A1 | Prodrug Comprising a Drug Linker Conjugate | ASCENDIS PHARMA A/S (DK) | 2020-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200046725-A1 | Prodrug Comprising a Drug Linker Conjugate | H1-0, H1-3, H1-2 | EPHX1 1697/4885TSHR 994/4885EPHX2 1085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.