Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | BCL9 | O00512 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18291847 | 0.87 | CA14 (0.36) | ALDH1A1FAAHGAACA14L3MBTL1 | |
| SCHEMBL18291923 | 0.86 | MGLL (0.51) | MGLLALDH1A1SMN1; SMN2FAAHTRPV1 | |
| SCHEMBL26616595 | 0.84 | MGLL (0.66) | MGLLFAAHTRPV1GAACA14 | |
| SCHEMBL12917703 | 0.84 | MGLL (0.61) | MGLLALDH1A1SMN1; SMN2FAAHTRPV1 | |
| SCHEMBL25919975 | 0.83 | MGLL (0.48) | MGLLALDH1A1SMN1; SMN2FAAHTRPV1 | |
| SCHEMBL18712547 | 0.81 | MGLL (0.57) | MGLLALDH1A1SMN1; SMN2FAAHTRPV1 | |
| SCHEMBL18291881 | 0.80 | CA14 (0.41) | SMN1; SMN2CA14L3MBTL1 | |
| SCHEMBL14708941 | 0.79 | CA14 (0.45) | CA14L3MBTL1 | |
| SCHEMBL16141285 | 0.79 | CA14 (0.45) | CA14L3MBTL1 | |
| SCHEMBL12917526 | 0.78 | CA14 (0.39) | SMN1; SMN2CA14L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016193371-A1 | PRODRUGS COMPRISING AN GLP-1/GLUCAGON DUAL AGONIST LINKER HYALURONIC ACID CONJUGATE | SANOFI (FR) | 2016-12-08 | — | — | WO | disclosed |
| US-9133276-B2 | Prodrugs comprising an exendin linker conjugate | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2015-09-15 | — | — | US | disclosed |