Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | FAAH | O00519 | 6/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | CKS1B | P61024 | 1/20 | 0.33 |
| ▸ | SKP1 | P63208 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17080678 | 0.87 | MGLL (0.46) | CA14L3MBTL1FAAHGAAALDH1A1 | |
| SCHEMBL18291881 | 0.82 | CA14 (0.41) | CA14L3MBTL1CKS1BSKP1SKP2 | |
| SCHEMBL14708941 | 0.81 | CA14 (0.45) | CA14L3MBTL1CKS1BSKP1SKP2 | |
| SCHEMBL16141285 | 0.81 | CA14 (0.45) | CA14L3MBTL1CKS1BSKP1SKP2 | |
| SCHEMBL12917526 | 0.80 | CA14 (0.39) | CA14L3MBTL1CKS1BSKP1SKP2 | |
| SCHEMBL14709092 | 0.79 | CA14 (0.38) | CA14L3MBTL1CKS1BSKP1SKP2 | |
| SCHEMBL16330568 | 0.78 | HDAC3 (0.40) | CA14L3MBTL1HDAC3HDAC1HDAC2 | |
| SCHEMBL45876 | 0.78 | MEN1 (0.41) | CA14L3MBTL1IDO1HDAC3HDAC1 | |
| SCHEMBL12917528 | 0.77 | KIF11 (0.46) | — | |
| SCHEMBL20230560 | 0.76 | KIF11 (0.39) | NPC1GAARAB9ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016193371-A1 | PRODRUGS COMPRISING AN GLP-1/GLUCAGON DUAL AGONIST LINKER HYALURONIC ACID CONJUGATE | SANOFI (FR) | 2016-12-08 | — | — | WO | disclosed |