Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17081319 | 0.81 | PAM (0.46) | MAPTMAOBHDAC1HDAC8HDAC6 | |
| SCHEMBL19879764 | 0.80 | GRIK1 (0.39) | GRIK1GRIK2MAPTNPC1RAB9A | |
| SCHEMBL17080953 | 0.80 | GRIK1 (0.39) | GRIK1GRIK2MAPTNPC1RAB9A | |
| SCHEMBL18112877 | 0.79 | GRIK1 (0.50) | GRIK1GRIK2MAPTNPC1RAB9A | |
| SCHEMBL18112878 | 0.79 | GRIK1 (0.50) | GRIK1GRIK2MAPTNPC1RAB9A | |
| SCHEMBL17080955 | 0.78 | MAOB (0.46) | GRIK1GRIK2MAOBHDAC1HDAC8 | |
| SCHEMBL1788686 | 0.74 | GSR (0.46) | GRIK1GRIK2MAPTNPC1RAB9A | |
| SCHEMBL7125844 | 0.74 | NPSR1 (0.53) | MAPTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL17080950 | 0.71 | MEN1 (0.43) | GRIK1GRIK2MAPTNPC1RAB9A | |
| SCHEMBL16803423 | 0.70 | NPSR1 (0.50) | MAPTNPC1RAB9ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9896479-B2 | Functionalized naphthalene fluorophores | Kay M. Brummond (US) | 2018-02-20 | — | — | US | disclosed |
| US-9896479-B2 | Functionalized naphthalene fluorophores | Kay M. Brummond (US) | 2018-02-20 | — | — | US | disclosed |
| US-20160046666-A1 | FUNCTIONALIZED NAPHTHALENE FLUOROPHORES | BRUMMOND, KAY M | 2016-02-18 | — | — | US | disclosed |
| US-20160046666-A1 | FUNCTIONALIZED NAPHTHALENE FLUOROPHORES | BRUMMOND, KAY M | 2016-02-18 | — | — | US | disclosed |
| US-9133234-B2 | Functionalized naphthalene fluorophores | Brummond, Kay M. (US) | 2015-09-15 | — | — | US | disclosed |
| US-9133234-B2 | Functionalized naphthalene fluorophores | Brummond, Kay M. (US) | 2015-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160046666-A1 | FUNCTIONALIZED NAPHTHALENE FLUOROPHORES | NCL, SNW1, NEK1 | GRIK1 2584/4885GRIK2 3261/4885MAPT 2209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.