SCHEMBL1788686

SCHEMBL1788686

C=C(CCC=Cc1ccccc1Cl)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.46
GRIK1 P39086 1/20 0.46
GRIK2 Q13002 1/20 0.46
MAPT P10636 6/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
MAOB P27338 2/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
LMNA P02545 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
HPGD P15428 2/20 0.42
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
HSP90AA1 P07900 1/20 0.40
ALDH1A1 P00352 2/20 0.40
POLB P06746 2/20 0.40
TRPA1 O75762 1/20 0.39
TRPM8 Q7Z2W7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18112877 0.84 GRIK1 (0.50) GSRGRIK1GRIK2MAPTNPC1
SCHEMBL18112878 0.84 GRIK1 (0.50) GSRGRIK1GRIK2MAPTNPC1
SCHEMBL1787953 0.83 NFKB1 (0.49) MAPTNPC1RAB9ALMNATRPA1
SCHEMBL1790938 0.82 MAPT (0.44) MAPTNPC1RAB9AMAOBLMNA
SCHEMBL1791129 0.82 HSD11B1 (0.47) MAPTHDAC1HDAC8HDAC6MEN1
SCHEMBL1793023 0.82 ALDH1A1 (0.42) NPC1RAB9ALMNASMN1; SMN2ALDH1A1
SCHEMBL5965835 0.80 MAPT (0.55) MAPTNPC1RAB9AMAOBLMNA
SCHEMBL699686 0.79 PAM (0.52) GRIK1GRIK2MAPTMAOBHDAC1
SCHEMBL8115998 0.79 PAM (0.52) GRIK1GRIK2MAPTMAOBHDAC1
SCHEMBL1788985 0.78 NFE2L2 (0.52) GRIK1GRIK2MAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110123929-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, PRODUCTION METHOD FOR THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT FUJIFILM CORPORATION (JP) 2011-05-26 US disclosed
US-7041416-B2 Photosensitive resin composition, transfer material, image forming method, color filter and producing method thereof and photomask and producing method thereof FUJI PHOTO FILM CO., LTD. (JP) 2006-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123929-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, PRODUCTION METHOD FOR THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT PPOX, CRY2, HCCS GSR 4035/4885GRIK1 4225/4885GRIK2 4251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.