Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1707702 | 0.87 | LTB4R (0.30) | — | |
| SCHEMBL1708570 | 0.87 | LTB4R (0.30) | — | |
| SCHEMBL10012574 | 0.83 | FFAR1 (0.42) | — | |
| SCHEMBL1708356 | 0.80 | AKR1B1 (0.31) | — | |
| SCHEMBL1708633 | 0.78 | FFAR1 (0.42) | — | |
| SCHEMBL1708578 | 0.76 | KDM6B (0.32) | — | |
| SCHEMBL1707861 | 0.75 | LTB4R (0.31) | — | |
| SCHEMBL1707739 | 0.74 | — | — | |
| SCHEMBL1708193 | 0.74 | — | — | |
| SCHEMBL1707982 | 0.74 | FFAR1 (0.33) | S1PR1DRD2DRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |