Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 5/20 | 0.32 |
| ▸ | HTR2A | P28223 | 4/20 | 0.32 |
| ▸ | DRD3 | P35462 | 4/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD5 | P21918 | 1/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | FADS1 | O60427 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1707705 | 0.85 | LTB4R (0.33) | HTR2ALTB4RLTB4R2 | |
| SCHEMBL1708702 | 0.82 | P2RX7 (0.35) | FFAR1CYP2C8DRD2HTR2ADRD3 | |
| SCHEMBL10010874 | 0.80 | FFAR1 (0.46) | FFAR1 | |
| SCHEMBL1708097 | 0.74 | S1PR1 (0.33) | DRD2DRD1DRD4DRD5S1PR1 | |
| SCHEMBL1707821 | 0.74 | KDM4C (0.37) | FFAR1LTB4RLTB4R2 | |
| SCHEMBL26789976 | 0.70 | FADS1 (0.46) | FADS1 | |
| SCHEMBL204322 | 0.69 | LTB4R (0.40) | LTB4RLTB4R2 | |
| SCHEMBL205688 | 0.69 | LTB4R (0.40) | LTB4RLTB4R2 | |
| SCHEMBL17431399 | 0.69 | LTB4R (0.40) | LTB4RLTB4R2 | |
| SCHEMBL1708703 | 0.69 | FFAR1 (0.35) | FFAR1CYP2C8P2RX7FADS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |