Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.32 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | UGCG | Q16739 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10009995 | 0.88 | FFAR1 (0.39) | — | |
| SCHEMBL1708126 | 0.87 | FFAR1 (0.33) | GUCY1A1GUCY1B1TRPV1UGCGDRD2 | |
| SCHEMBL1708425 | 0.85 | NTRK1 (0.36) | GUCY1A1GUCY1B1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL1708291 | 0.85 | ALDH1A1 (0.32) | ALDH1A1MAPTMAPK1 | |
| SCHEMBL1708168 | 0.84 | NTRK1 (0.36) | GUCY1A1GUCY1B1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL1707942 | 0.84 | NTRK1 (0.36) | GUCY1A1GUCY1B1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL1708667 | 0.84 | ALDH1A1 (0.32) | ALDH1A1MAPTMAPK1 | |
| SCHEMBL1708661 | 0.83 | MAPT (0.33) | L3MBTL1ALDH1A1MAPTMAPK1 | |
| SCHEMBL1708620 | 0.83 | ALDH1A1 (0.32) | ALDH1A1MAPTMAPK1 | |
| SCHEMBL1708673 | 0.83 | MAPT (0.33) | L3MBTL1ALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |