Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1708678 | 0.94 | FFAR1 (0.46) | FFAR1MTNR1AMTNR1BPPARDPPARG | |
| SCHEMBL1708300 | 0.92 | FFAR1 (0.38) | FFAR1PPARDPPARGPPARAMAPT | |
| SCHEMBL1708113 | 0.92 | FFAR1 (0.40) | FFAR1POLBGAANPC1PPARD | |
| SCHEMBL1708140 | 0.91 | FFAR1 (0.38) | FFAR1POLBGAANPC1PPARD | |
| SCHEMBL10291805 | 0.89 | MTNR1A (0.39) | FFAR1MTNR1AMTNR1BNPC1MAPT | |
| SCHEMBL10292315 | 0.89 | MTNR1A (0.39) | FFAR1MTNR1AMTNR1BNPC1MAPT | |
| SCHEMBL1708680 | 0.88 | MTNR1A (0.39) | FFAR1MTNR1AMTNR1BPOLBNPC1 | |
| SCHEMBL1708164 | 0.86 | FFAR1 (0.37) | FFAR1POLBGAANPC1PPARD | |
| SCHEMBL10010980 | 0.85 | FFAR1 (0.45) | FFAR1PPARDPPARGPPARA | |
| SCHEMBL1708439 | 0.85 | FFAR1 (0.40) | FFAR1POLBGAANPC1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |