Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.41 |
| ▸ | EBP | Q15125 | 5/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | FPR1 | P21462 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | PTGES | O14684 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL550444 | 1.00 | HSD11B1 (0.41) | HSD11B1EBPHTR7FPR1FPR2 | |
| SCHEMBL550443 | 1.00 | HSD11B1 (0.41) | HSD11B1EBPHTR7FPR1FPR2 | |
| SCHEMBL550496 | 0.87 | HSD11B1 (0.41) | HSD11B1EBPHTR7FPR1FPR2 | |
| SCHEMBL17082135 | 0.87 | HSD11B1 (0.41) | HSD11B1EBPHTR7FPR1FPR2 | |
| SCHEMBL17082030 | 0.86 | HTR7 (0.42) | HSD11B1HTR7HCRTR2 | |
| SCHEMBL550819 | 0.86 | HTR7 (0.42) | HSD11B1HTR7HCRTR2 | |
| SCHEMBL550818 | 0.86 | HTR7 (0.42) | HSD11B1HTR7HCRTR2 | |
| SCHEMBL549280 | 0.85 | HSD11B1 (0.43) | HSD11B1EBPHTR7FPR1FPR2 | |
| SCHEMBL549281 | 0.85 | HSD11B1 (0.43) | HSD11B1EBPHTR7FPR1FPR2 | |
| SCHEMBL4570105 | 0.85 | HSD11B1 (0.41) | HSD11B1EBPHTR7FPR1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812005-B1 | LACTAM COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2015-09-16 | — | — | EP | disclosed |