SCHEMBL17084378

SCHEMBL17084378

CCCC1(CCC)c2ccccc2-c2ccc(/C(=N/O)c3cccc4ccccc34)cc21

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 10/20 0.35
▸ CASP3 P42574 1/20 0.34
▸ GFER P55789 1/20 0.34
▸ SENP8 Q96LD8 1/20 0.34
▸ SENP7 Q9BQF6 1/20 0.34
▸ SENP6 Q9GZR1 1/20 0.34
▸ PDK2 Q15119 6/20 0.33
▸ CBX7 O95931 1/20 0.33
▸ CDYL Q9Y232 1/20 0.33
▸ CDY1; CDY1B Q9Y6F8 1/20 0.33
▸ APEX1 P27695 1/20 0.33
▸ CNR1 P21554 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30529689 0.85 PDK2 (0.35) PDK2APEX1
SCHEMBL17084377 0.85 CNR2 (0.47) CNR2CNR1
SCHEMBL17084343 0.84 NPC1 (0.36) CNR2PDK2CBX7CDYLCDY1; CDY1B
SCHEMBL19832350 0.82 CNR2 (0.38) CNR2PDK2CBX7CDYLCDY1; CDY1B
SCHEMBL18122993 0.78 CNR2 (0.36) CNR2PDK2CBX7CDYLCDY1; CDY1B
SCHEMBL17084358 0.78 KDM4E (0.40) CASP3GFERSENP8SENP7SENP6
SCHEMBL19186318 0.76 KMT2A (0.39) GFERPDK2
SCHEMBL17084308 0.76 CNR2 (0.41) CNR2CNR1
SCHEMBL18812932 0.73 APEX1 (0.36) PDK2APEX1
SCHEMBL18812934 0.73 APEX1 (0.36) PDK2APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9684238-B2 Fluorene-type compound, photopolymerization initiator comprising said fluorene-type compound, and photosensitive composition containing said photopolymerization initiator TOKYO OHKA KOGYO CO., LTD. (JP) 2017-06-20 — — US disclosed
US-9684238-B2 Fluorene-type compound, photopolymerization initiator comprising said fluorene-type compound, and photosensitive composition containing said photopolymerization initiator TOKYO OHKA KOGYO CO., LTD. (JP) 2017-06-20 — — US disclosed
US-20150259321-A1 FLUORENE-TYPE COMPOUND, PHOTOPOLYMERIZATION INITIATOR COMPRISING SAID FLUORENE-TYPE COMPOUND, AND PHOTOSENSITIVE COMPOSITION CONTAINING SAID PHOTOPOLYMERIZATION INITIATOR DAITO CHEMIX CORPORATION (JP) 2015-09-17 — — US disclosed
US-20150259321-A1 FLUORENE-TYPE COMPOUND, PHOTOPOLYMERIZATION INITIATOR COMPRISING SAID FLUORENE-TYPE COMPOUND, AND PHOTOSENSITIVE COMPOSITION CONTAINING SAID PHOTOPOLYMERIZATION INITIATOR DAITO CHEMIX CORPORATION (JP) 2015-09-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150259321-A1 FLUORENE-TYPE COMPOUND, PHOTOPOLYMERIZATION INITIATOR COMPRISING SAID FLUORENE-TYPE COMPOUND, AND PHOTOSENSITIVE COMPOSITION CONTAINING SAID PHOTOPOLYMERIZATION INITIATOR AFF1, AFF2, FTO CNR2 766/4885CASP3 3653/4885GFER 265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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