Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 7/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 7/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 6/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1706792 | 1.00 | KAT2B (0.51) | KAT2BKDM4EKMT2ACHRNB4CHRNA3 | |
| SCHEMBL1708336 | 0.91 | KAT2B (0.51) | KAT2BKDM4EKMT2ACHRNB4CHRNA3 | |
| SCHEMBL1708335 | 0.91 | KAT2B (0.51) | KAT2BKDM4EKMT2ACHRNB4CHRNA3 | |
| SCHEMBL1707682 | 0.89 | KAT2B (0.49) | KAT2BKDM4EKMT2ACHRNB4CHRNA3 | |
| SCHEMBL1707685 | 0.89 | KAT2B (0.49) | KAT2BKDM4EKMT2ACHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL1707463 | 0.88 | KAT2B (0.49) | KAT2BKDM4EKMT2ACHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL1707465 | 0.88 | KAT2B (0.49) | KAT2BKDM4EKMT2ACHRNB4CHRNA3 | |
| SCHEMBL1707692 | 0.87 | KAT2B (0.40) | KAT2BKMT2A | |
| SCHEMBL4229392 | 0.87 | KAT2B (0.45) | KAT2BKDM4EKMT2ASIGMAR1 | |
| SCHEMBL4229385 | 0.87 | KAT2B (0.45) | KAT2BKDM4EKMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981877-B1 | N-HYDROXYACRYLAMIDE COMPOUNDS | ASTELLAS PHARMA INC (JP) | 2012-04-18 | — | — | EP | disclosed |