Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1706904 | 0.95 | JAK2 (0.41) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL1708479 | 0.90 | KAT2B (0.41) | KAT2BLTA4HKMT2AROCK2CCR2 | |
| SCHEMBL1708477 | 0.90 | KAT2B (0.41) | KAT2BLTA4HKMT2AROCK2CCR2 | |
| SCHEMBL1707646 | 0.89 | ROCK2 (0.40) | KAT2BLTA4HKMT2AROCK2CCR2 | |
| SCHEMBL1707426 | 0.89 | HDAC1 (0.42) | KAT2BLTA4HKMT2AJAK2JAK1 | |
| SCHEMBL1707419 | 0.89 | HDAC1 (0.42) | KAT2BLTA4HKMT2AJAK2JAK1 | |
| Hydrochloric Acid SCHEMBL1707668 | 0.88 | HDAC1 (0.41) | KAT2BLTA4HKMT2AJAK2JAK1 | |
| Hydrochloric Acid SCHEMBL1707666 | 0.88 | HDAC1 (0.41) | KAT2BLTA4HKMT2AJAK2JAK1 | |
| SCHEMBL1708478 | 0.87 | KAT2B (0.51) | KAT2BKMT2A | |
| SCHEMBL1706792 | 0.87 | KAT2B (0.51) | KAT2BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981877-B1 | N-HYDROXYACRYLAMIDE COMPOUNDS | ASTELLAS PHARMA INC (JP) | 2012-04-18 | — | — | EP | disclosed |