Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20432855 | 0.90 | HDAC6 (0.49) | HDAC1HDAC6HDAC8HDAC10ADAM10 | |
| SCHEMBL17078940 | 0.90 | HDAC6 (0.49) | HDAC1HDAC6HDAC8HDAC10ADAM10 | |
| SCHEMBL17086801 | 0.84 | HDAC1 (0.47) | HDAC1HDAC6HDAC8HDAC10HDAC4 | |
| SCHEMBL17086800 | 0.83 | HIF1A (0.44) | HDAC1HDAC6HDAC8MMP2HDAC4 | |
| SCHEMBL17086791 | 0.82 | HDAC6 (0.46) | HDAC1HDAC6HDAC8HDAC4KCNH2 | |
| SCHEMBL17078537 | 0.82 | HDAC1 (0.38) | HDAC1HDAC6ADAM10MMP2MMP9 | |
| SCHEMBL20421063 | 0.80 | HDAC1 (0.37) | HDAC1HDAC6ADAM10MMP2MMP9 | |
| SCHEMBL17078694 | 0.80 | HDAC6 (0.64) | HDAC1HDAC6HDAC8HDAC10HDAC4 | |
| SCHEMBL17078942 | 0.80 | HDAC6 (0.49) | HDAC1HDAC6HDAC4KCNH2 | |
| SCHEMBL20432796 | 0.80 | HDAC6 (0.49) | HDAC1HDAC6HDAC4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015137750-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2015-09-17 | — | — | WO | disclosed |