Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 3/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17078735 | 0.88 | HDAC1 (0.58) | HDAC1PKMHDAC6NAMPTALDH1A1 | |
| SCHEMBL17078837 | 0.81 | LMNA (0.49) | HDAC1PKMNAMPTALDH1A1GAA | |
| SCHEMBL20420901 | 0.77 | PKM (0.52) | PKMNAMPTALDH1A1MAPTMMP13 | |
| SCHEMBL17078523 | 0.75 | HDAC1 (0.57) | HDAC1HDAC6NAMPTHDAC8MAPT | |
| SCHEMBL17086794 | 0.74 | HDAC1 (0.53) | HDAC1HDAC6HDAC8 | |
| SCHEMBL20432707 | 0.74 | HDAC1 (0.57) | HDAC1HDAC6ALDH1A1 | |
| SCHEMBL20432705 | 0.74 | HDAC1 (0.57) | HDAC1HDAC6ALDH1A1 | |
| SCHEMBL20432848 | 0.74 | HDAC1 (0.54) | HDAC1PKMHDAC6ALDH1A1GAA | |
| SCHEMBL17079073 | 0.74 | HDAC1 (0.54) | HDAC1PKMHDAC6ALDH1A1GAA | |
| SCHEMBL20432638 | 0.74 | HDAC6 (0.58) | HDAC1HDAC6HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015137750-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2015-09-17 | — | — | WO | disclosed |