Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.68 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | CCR1 | P32246 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | FPR3 | P25089 | 1/20 | 0.45 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17079000 | 0.87 | HDAC1 (0.76) | HDAC1HDAC6PTGDR2HDAC4KCNH2 | |
| SCHEMBL20432797 | 0.87 | HDAC1 (0.76) | HDAC1HDAC6PTGDR2HDAC4KCNH2 | |
| SCHEMBL20432708 | 0.87 | PTGDR2 (0.52) | HDAC1HDAC6PTGDR2HDAC4KCNH2 | |
| SCHEMBL20432807 | 0.85 | HDAC1 (0.76) | HDAC1HDAC6HDAC4KCNH2HDAC8 | |
| SCHEMBL17079047 | 0.81 | HDAC1 (1.00) | HDAC1HDAC6HDAC4KCNH2HDAC8 | |
| SCHEMBL17086787 | 0.81 | HDAC1 (0.61) | HDAC1HDAC6PTGDR2HDAC4KCNH2 | |
| SCHEMBL17078583 | 0.81 | HDAC1 (0.76) | HDAC1HDAC6HDAC4KCNH2MEN1 | |
| SCHEMBL18690249 | 0.79 | HDAC1 (0.76) | HDAC1HDAC6HDAC4KCNH2HDAC8 | |
| SCHEMBL17086810 | 0.78 | HDAC1 (0.56) | HDAC1HDAC6HDAC4KCNH2HDAC8 | |
| SCHEMBL17079048 | 0.76 | HDAC1 (0.72) | HDAC1HDAC6HDAC4KCNH2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015137750-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2015-09-17 | — | — | WO | disclosed |