Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1708288 | 0.89 | FFAR1 (0.35) | — | |
| SCHEMBL10009726 | 0.87 | FFAR1 (0.36) | — | |
| SCHEMBL10010935 | 0.87 | FFAR1 (0.36) | — | |
| SCHEMBL10010835 | 0.87 | FFAR1 (0.36) | — | |
| SCHEMBL1708117 | 0.85 | LMNA (0.35) | TSHR | |
| SCHEMBL1708047 | 0.85 | LMNA (0.35) | TSHR | |
| SCHEMBL1707935 | 0.85 | LMNA (0.35) | TSHR | |
| SCHEMBL1707928 | 0.83 | — | — | |
| SCHEMBL1707993 | 0.82 | SCN9A (0.30) | — | |
| SCHEMBL1708326 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |