SCHEMBL17088158

SCHEMBL17088158

CCCC[Si](CCC)(CCC)O[Si](CCC)(CCC)CCCC

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
LMNA P02545 1/20 0.33
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5940456 0.94 TSHR (0.38) TSHRLMNATHRB
SCHEMBL301688 0.87
SCHEMBL6017704 0.85 TSHR (0.41) TSHRLMNATHRB
SCHEMBL26656732 0.82 TSHR (0.33) TSHRLMNATHRB
SCHEMBL4959288 0.82 TSHR (0.47) TSHRLMNATHRB
SCHEMBL9859881 0.82 TSHR (0.47) TSHRLMNATHRB
SCHEMBL7036618 0.82 TSHR (0.47) TSHRLMNATHRB
SCHEMBL11024773 0.82 TSHR (0.47) TSHRLMNATHRB
SCHEMBL8409968 0.81 DNM1 (0.38) TSHR
SCHEMBL8409957 0.81 DNM1 (0.43) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230203368-A1 RAPID THICKENING OF AMINOSILICONES TO PROMOTE EMULSION STABILITY AND ADHESION OF UV-CURABLE QUANTUM DOT ENHANCEMENT FILM EMULSIONS NANOSYS, INC. (US) 2023-06-29 US disclosed
US-20180223182-A1 RAPID THICKENING OF AMINOSILICONES TO PROMOTE EMULSION STABILITY AND ADHESION OF UV-CURABLE QUANTUM DOT ENHANCEMENT FILM EMULSIONS NANOSYS, INC. (US) 2018-08-09 US disclosed
US-9139770-B2 Silicone ligands for stabilizing quantum dot films NANOSYS, INC. (US) 2015-09-22 US disclosed