SCHEMBL1708818

SCHEMBL1708818

CC(=O)NCc1cc(N)ccc1N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.41
EPHX2 P34913 1/20 0.40
NR1H4 Q96RI1 1/20 0.40
SETDB1 Q15047 4/20 0.40
ALDH1A1 P00352 3/20 0.40
KMT2A Q03164 2/20 0.40
HDAC1 Q13547 2/20 0.39
POLB P06746 2/20 0.39
MAPT P10636 2/20 0.39
MEN1 O00255 1/20 0.39
USP2 O75604 1/20 0.39
THRB P10828 1/20 0.39
PKM P14618 1/20 0.39
APEX1 P27695 1/20 0.39
RECQL P46063 1/20 0.39
BLM P54132 1/20 0.39
MCL1 Q07820 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MTNR1A P48039 1/20 0.39
NQO2 P16083 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6679209 0.98 KMT2A (0.42) NPSR1EPHX2NR1H4SETDB1ALDH1A1
SCHEMBL6272499 0.85 CD274 (0.39) EPHX2NR1H4ALDH1A1MAPTBLM
Hydrochloric Acid SCHEMBL7097957 0.84 CD274 (0.38) EPHX2NR1H4ALDH1A1KMT2APOLB
SCHEMBL9826470 0.84 PRKCI (0.50) NPSR1EPHX2NR1H4SETDB1ALDH1A1
SCHEMBL4625409 0.83 MTNR1B (0.46) NPSR1ALDH1A1KMT2AMAPTMEN1
SCHEMBL4856579 0.80 MTNR1A (0.49) ALDH1A1POLBMAPTMTNR1AKDM4E
Hydrochloric Acid SCHEMBL6270873 0.80 CD274 (0.36) EPHX2NR1H4KMT2APOLBMAPT
SCHEMBL6675975 0.79 NQO2 (0.48) ALDH1A1KMT2APOLBMAPTMEN1
SCHEMBL10416108 0.78 HPGD (0.57) NPSR1SETDB1ALDH1A1HDAC1MTNR1A
SCHEMBL12330489 0.78 KDM4A (0.45) EPHX2NR1H4HDAC1NQO2HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150062519-A1 ALIGNMENT FILM, COMPOSITION FOR FORMING ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE JAPAN DISPLAY INC (JP) 2015-03-05 US disclosed
US-8906474-B2 Alignment film, composition for forming alignment film and liquid crystal display device JAPAN DISPLAY INC. (JP) 2014-12-09 US disclosed
US-20120088040-A1 ALIGNMENT FILM, COMPOSITION FOR FORMING ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE MAGNOLIA WHITE CORPORATION (JP) 2012-04-12 US disclosed
US-20120088040-A1 ALIGNMENT FILM, COMPOSITION FOR FORMING ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE MAGNOLIA WHITE CORPORATION (JP) 2012-04-12 US disclosed