SCHEMBL339009

SCHEMBL339009

O=C(O)c1cccc(OCc2ccccc2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 8/20 1.00
SRD5A2 P31213 1/20 0.80
MAOB P27338 1/20 0.77
MRGPRX4 Q96LA9 4/20 0.75
MEN1 O00255 1/20 0.75
KMT2A Q03164 1/20 0.75
NR1H4 Q96RI1 1/20 0.74
SMPD1 P17405 1/20 0.72
NR4A1 P22736 1/20 0.71
NR4A3 Q92570 1/20 0.71
FFAR1 O14842 1/20 0.70
PTPN1 P18031 1/20 0.68
TSHR P16473 1/20 0.68
SMN1; SMN2 Q16637 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30207018 1.00 NR4A2 (1.00) NR4A2SRD5A2MAOBMRGPRX4MEN1
Hydrochloric Acid SCHEMBL4748074 0.98 NR4A2 (0.97) NR4A2SRD5A2MAOBMRGPRX4MEN1
SCHEMBL1122713 0.97 NR4A2 (0.94) NR4A2SRD5A2MAOBMRGPRX4MEN1
SCHEMBL1123155 0.95 NR4A2 (0.91) NR4A2SRD5A2MAOBMRGPRX4MEN1
SCHEMBL4406160 0.93 NR4A2 (0.87) NR4A2SRD5A2MRGPRX4SMN1; SMN2
SCHEMBL30994900 0.90 NR4A2 (0.82) NR4A2SRD5A2MAOBMRGPRX4MEN1
SCHEMBL27815839 0.90 NR4A2 (0.82) NR4A2SRD5A2MAOBMRGPRX4MEN1
SCHEMBL4138759 0.90 NR4A2 (0.81) NR4A2MRGPRX4SMN1; SMN2
SCHEMBL7908051 0.90 SRD5A2 (0.85) NR4A2SRD5A2MAOBMRGPRX4MEN1
SCHEMBL3442746 0.88 NR4A2 (0.79) NR4A2SRD5A2MAOBMRGPRX4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 366 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017132775-A1 NOVEL COMPOSITIONS AND METHODS FOR THE TREATMENT OF LEIOMYOMA VITEAVA PHARMACEUTICALS INC. (CA) 2017-08-10 WO claimed
CN-1732161-A 1,3-diamino-2-hydroxypropane pro-drug derivatives ELAN PHARM INC (US) 2006-02-08 CN claimed
CN-1132508-A Piperazine derivatives REORDATI IND CHIMICA E FARMACE (CH) 1996-10-02 CN claimed
JP-63091347-A None JP disclosed
US-12600703-B2 Methods of synthesizing farnesyl dibenzodiazepinones AMO PHARMA LTD. (GB) 2026-04-14 US disclosed
US-12534457-B2 Heteroaryl derivative compounds, and uses thereof VORONOI INC. (KR) 2026-01-27 US disclosed
US-20260021192-A1 PROTEINS HAVING A COVALENT WARHEAD TOPAZ THERAPEUTICS INC (US) 2026-01-22 US disclosed
US-12528799-B2 Heteroaryl derivative compounds, and uses thereof VORONOI INC. (KR) 2026-01-20 US disclosed
US-20250214974-A1 INHIBITING MONOACYLGLYCEROL LIPASE (MAGL) PSY THERAPEUTICS, INC. (US) 2025-07-03 US disclosed
US-12286421-B2 Inhibiting monoacylglycerol lipase (MAGL) PSY THERAPEUTICS, INC. (US) 2025-04-29 US disclosed
US-20250084065-A1 INHIBITING MONOACYLGLYCEROL LIPASE (MAGL) PSY THERAPEUTICS, INC. (US) 2025-03-13 US disclosed
EP-0135838-B1 3-PHENYL-4-METHOXYCARBONYL PYRAZOLES, PROCESS FOR THEIR PREPARATION AND THEIR USE AGAINST PLANT GROWTH BASF Aktiengesellschaft (DE) 1990-04-18 EP disclosed
JP-S6391347-A PRODUCTION OF HYDROXYANTHRAQUINONE DERIVATIVE MITSUBISHI KASEI CORP 1988-04-22 JP disclosed
US-4537617-A HEBICIDES BASF AKTIENGESELLSCHAFT (DE) 1985-08-27 US disclosed
EP-0135838-A2 3-Phenyl-4-methoxycarbonyl pyrazoles, process for their preparation and their use against plant growth BASF Aktiengesellschaft (DE) 1985-04-03 EP disclosed
US-4386031-A ANTICOAGULANTS; ANTIALLERGENS; ANTINFLAM-MATORY AND ANTILIPEMIC AGENTS; ANTIHISTAMINES; CARDIOVASCULAR DISORDERS A. NATTERMANN & CIE GMBH (DE) 1983-05-31 US disclosed
US-4235913-A ANALGESICS, TRANQUILIZERS PFIZER INC. (US) 1980-11-25 US disclosed
US-4165323-A ANALGESICS, TRANQUILIZERS PFIZER INC. (US) 1979-08-21 US disclosed
US-4118559-A CNS AGENTS, ANALGESICS, TRANQUILIZERS PFIZER INC. (US) 1978-10-03 US disclosed
US-3953595-A Substituted benzoic acid hypolipemic agents PFIZER INC. (US) 1976-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214974-A1 INHIBITING MONOACYLGLYCEROL LIPASE (MAGL) MGLL, PNLIP, LIPC NR4A2 4573/4885SRD5A2 3568/4885MAOB 491/4885
US-12528799-B2 Heteroaryl derivative compounds, and uses thereof ERBB2, EGFR, ERBB3 NR4A2 267/4885SRD5A2 733/4885MAOB 3077/4885
US-12534457-B2 Heteroaryl derivative compounds, and uses thereof ERBB2, EGFR, ERBB3 NR4A2 2421/4885SRD5A2 1759/4885MAOB 2014/4885
US-20250084065-A1 INHIBITING MONOACYLGLYCEROL LIPASE (MAGL) MGLL, PNLIP, LPL NR4A2 2851/4885SRD5A2 1843/4885MAOB 620/4885
US-12286421-B2 Inhibiting monoacylglycerol lipase (MAGL) MGLL, PNLIP, LIPC NR4A2 4573/4885SRD5A2 3568/4885MAOB 491/4885
US-12600703-B2 Methods of synthesizing farnesyl dibenzodiazepinones NR1H2, NR1H3, NR1H4 NR4A2 715/4885SRD5A2 170/4885MAOB 2969/4885
US-20260021192-A1 PROTEINS HAVING A COVALENT WARHEAD RIOX2, ORC3, DCLRE1A NR4A2 1989/4885SRD5A2 1430/4885MAOB 3262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.