Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 8/20 | 1.00 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.80 |
| ▸ | MAOB | P27338 | 1/20 | 0.77 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.75 |
| ▸ | MEN1 | O00255 | 1/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.75 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.74 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.72 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.71 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.71 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.70 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL339009 | 1.00 | NR4A2 (1.00) | NR4A2SRD5A2MAOBMRGPRX4MEN1 | |
| Hydrochloric Acid SCHEMBL4748074 | 0.98 | NR4A2 (0.97) | NR4A2SRD5A2MAOBMRGPRX4MEN1 | |
| SCHEMBL1122713 | 0.97 | NR4A2 (0.94) | NR4A2SRD5A2MAOBMRGPRX4MEN1 | |
| SCHEMBL1123155 | 0.95 | NR4A2 (0.91) | NR4A2SRD5A2MAOBMRGPRX4MEN1 | |
| SCHEMBL4406160 | 0.93 | NR4A2 (0.87) | NR4A2SRD5A2MRGPRX4SMN1; SMN2 | |
| SCHEMBL30994900 | 0.90 | NR4A2 (0.82) | NR4A2SRD5A2MAOBMRGPRX4MEN1 | |
| SCHEMBL27815839 | 0.90 | NR4A2 (0.82) | NR4A2SRD5A2MAOBMRGPRX4MEN1 | |
| SCHEMBL4138759 | 0.90 | NR4A2 (0.81) | NR4A2MRGPRX4SMN1; SMN2 | |
| SCHEMBL7908051 | 0.90 | SRD5A2 (0.85) | NR4A2SRD5A2MAOBMRGPRX4MEN1 | |
| SCHEMBL3442746 | 0.88 | NR4A2 (0.79) | NR4A2SRD5A2MAOBMRGPRX4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117255792-A | Heteroaryl derivatives, process for preparing the same and pharmaceutical compositions comprising the same as active ingredient | 沃若诺伊公司 | 2023-12-19 | — | — | CN | disclosed |
| EP-3002280-B1 | CYCLIC TRIAZO AND DIAZO SODIUM CHANNEL BLOCKERS | UNIV GREENWICH (GB) | 2023-05-24 | — | — | EP | disclosed |
| CN-115835869-A | Process for the synthesis of nifedibenzodiazepinone | 阿默制药有限公司 | 2023-03-21 | — | — | CN | disclosed |