SCHEMBL17089048

SCHEMBL17089048

O=C(O)c1cc(C(=O)O)cc(-c2cccnc2)c1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMO O15229 2/20 0.77
MKNK1 Q9BUB5 6/20 0.71
MKNK2 Q9HBH9 6/20 0.71
ALDH1A1 P00352 3/20 0.60
APP P05067 1/20 0.60
GAA P10253 1/20 0.60
HCAR3 P49019 1/20 0.60
HCAR2 Q8TDS4 1/20 0.60
CYP2A6 P11509 2/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP19A1 P11511 1/20 0.53
DHODH Q02127 2/20 0.51
IP6K1 Q92551 1/20 0.51
IP6K3 Q96PC2 1/20 0.51
IP6K2 Q9UHH9 1/20 0.51
GLO1 Q04760 1/20 0.50
PIM1 P11309 1/20 0.50
PIM2 Q9P1W9 1/20 0.50
KDM4E B2RXH2 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29503876 1.00 KMO (0.77) KMOMKNK1MKNK2ALDH1A1APP
SCHEMBL10028699 0.96 KMO (0.77) KMOMKNK1MKNK2ALDH1A1APP
SCHEMBL13044190 0.93 KMO (0.73) KMOMKNK1MKNK2ALDH1A1APP
SCHEMBL5226019 0.89 KMO (0.67) KMOMKNK1MKNK2ALDH1A1APP
SCHEMBL14395132 0.89 KMO (0.67) KMOMKNK1MKNK2ALDH1A1APP
SCHEMBL5229566 0.89 KMO (0.67) KMOMKNK1MKNK2ALDH1A1APP
SCHEMBL19021036 0.88 KMO (0.66) KMOMKNK1MKNK2ALDH1A1APP
SCHEMBL28143431 0.88 KMO (0.61) KMOMKNK1MKNK2ALDH1A1APP
SCHEMBL1690466 0.87 KMO (0.75) KMOMKNK1MKNK2ALDH1A1APP
SCHEMBL29569537 0.87 KMO (1.00) KMOMKNK1MKNK2ALDH1A1APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116688953-A Iron-based metal-organic framework material, preparation method thereof and application thereof in separating methane and propane 吉林大学 2023-09-05 CN claimed
CN-114452946-A Method for simply and rapidly preparing high-valence transition metal-based metal organic framework device in situ 中国石油大学(华东) 2022-05-10 CN claimed
US-20240299905-A1 POST-SYNTHETIC FUNCTIONALIZATION OF POROUS MATERIALS UNITED STATES DEPARTMENT OF ENERGY 2024-09-12 US disclosed
CN-117049961-A Yeast dehydrogenase inhibitor derivative and synthesis method thereof 苏州君叶生物医药科技有限公司 2023-11-14 CN disclosed
CN-116688953-A Iron-based metal-organic framework material, preparation method thereof and application thereof in separating methane and propane 吉林大学 2023-09-05 CN disclosed
CN-116688953-A Iron-based metal-organic framework material, preparation method thereof and application thereof in separating methane and propane 吉林大学 2023-09-05 CN disclosed
CN-114452946-A Method for simply and rapidly preparing high-valence transition metal-based metal organic framework device in situ 中国石油大学(华东) 2022-05-10 CN disclosed
WO-2020184629-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME 日産化学株式会社 2020-09-17 WO disclosed
US-9139599-B1 2-periodic metal-organic frameworks (MOFs) as supermolecular building layers (SBLs) for making targeted 3-periodic MOFs UNIVERSITY OF SOUTH FLORIDA (US) 2015-09-22 US disclosed
CN-102382145-B Cobalt coordination compound containing 5-(3-pyridyl)-isophthalic acid organic ligands and preparation method for same UNIV NANCHANG HANGKONG 2013-09-25 CN disclosed
CN-102382145-B Cobalt coordination compound containing 5-(3-pyridyl)-isophthalic acid organic ligands and preparation method for same UNIV NANCHANG HANGKONG 2013-09-25 CN disclosed
CN-102382145-A Cobalt coordination compound containing 5-(3-pyridyl)-isophthalic acid organic ligands and preparation method for same UNIV NANCHANG HANGKONG 2012-03-21 CN disclosed
CN-102382145-A Cobalt coordination compound containing 5-(3-pyridyl)-isophthalic acid organic ligands and preparation method for same UNIV NANCHANG HANGKONG 2012-03-21 CN disclosed