Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 3/20 | 0.77 |
| ▸ | MKNK1 | Q9BUB5 | 5/20 | 0.71 |
| ▸ | MKNK2 | Q9HBH9 | 5/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | APP | P05067 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.60 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.60 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.51 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.51 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.51 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.50 |
| ▸ | DHODH | Q02127 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13044190 | 0.96 | KMO (0.73) | KMOMKNK1MKNK2ALDH1A1APP | |
| SCHEMBL17089048 | 0.96 | KMO (0.77) | KMOMKNK1MKNK2ALDH1A1APP | |
| SCHEMBL29503876 | 0.96 | KMO (0.77) | KMOMKNK1MKNK2ALDH1A1APP | |
| SCHEMBL10028681 | 0.89 | KMO (0.73) | KMOMKNK1MKNK2ALDH1A1APP | |
| SCHEMBL14395132 | 0.89 | KMO (0.67) | KMOMKNK1MKNK2ALDH1A1APP | |
| SCHEMBL5226019 | 0.89 | KMO (0.67) | KMOMKNK1MKNK2ALDH1A1APP | |
| SCHEMBL5229566 | 0.89 | KMO (0.67) | KMOMKNK1MKNK2ALDH1A1APP | |
| SCHEMBL29569537 | 0.87 | KMO (1.00) | KMOMKNK1MKNK2ALDH1A1APP | |
| SCHEMBL206541 | 0.87 | KMO (1.00) | KMOMKNK1MKNK2ALDH1A1APP | |
| SCHEMBL1690466 | 0.87 | KMO (0.75) | KMOMKNK1MKNK2ALDH1A1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8658795-B2 | Pyridinium boronic acid quenchers for use in analyte sensors | GLUMETRICS, INC. (US) | 2014-02-25 | — | — | US | disclosed |
| US-8658795-B2 | Pyridinium boronic acid quenchers for use in analyte sensors | GLUMETRICS, INC. (US) | 2014-02-25 | — | — | US | disclosed |
| US-20120208286-A1 | PYRIDINIUM BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS | GLUMETRICS, INC. (US) | 2012-08-16 | — | — | US | disclosed |
| US-20120208286-A1 | PYRIDINIUM BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS | GLUMETRICS, INC. (US) | 2012-08-16 | — | — | US | disclosed |
| US-8178676-B2 | Pyridinium boronic acid quenchers for use in analyte sensors | GLUMETRICS, INC. (US) | 2012-05-15 | — | — | US | disclosed |
| US-8178676-B2 | Pyridinium boronic acid quenchers for use in analyte sensors | GLUMETRICS, INC. (US) | 2012-05-15 | — | — | US | disclosed |
| US-20110171742-A1 | PYRIDINIUM BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS | GLUMETRICS, INC. (US) | 2011-07-14 | — | — | US | disclosed |
| US-20110171742-A1 | PYRIDINIUM BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS | GLUMETRICS, INC. (US) | 2011-07-14 | — | — | US | disclosed |
| US-7939664-B2 | Pyridinium boronic acid quenchers for use in analyte sensors | GLUMETRICS INC. (US) | 2011-05-10 | — | — | US | disclosed |
| US-7939664-B2 | Pyridinium boronic acid quenchers for use in analyte sensors | GLUMETRICS INC. (US) | 2011-05-10 | — | — | US | disclosed |
| EP-2147003-B1 | PYRIDINIUM BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS | GLUMETRICS INC (US) | 2011-04-20 | — | — | EP | disclosed |
| US-20080305009-A1 | PYRIDINIUM BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS | GLUMETRICS INC. (US) | 2008-12-11 | — | — | US | disclosed |
| US-20080305009-A1 | PYRIDINIUM BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS | GLUMETRICS INC. (US) | 2008-12-11 | — | — | US | disclosed |
| WO-2008137604-A1 | PYRIDINIUM BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS | GLUMETRICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208286-A1 | PYRIDINIUM BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS | BLVRB, PDXK, PNPO | KMO 339/4885MKNK1 3856/4885MKNK2 3960/4885 |
| US-20080305009-A1 | PYRIDINIUM BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS | BLVRB, PDXK, PNPO | KMO 339/4885MKNK1 3856/4885MKNK2 3960/4885 |
| US-20110171742-A1 | PYRIDINIUM BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS | BLVRB, PDXK, PNPO | KMO 339/4885MKNK1 3856/4885MKNK2 3960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.