Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 5/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565544 | 1.00 | TSHR (0.42) | TSHRMEN1KMT2ABRD4LMNA | |
| SCHEMBL13564870 | 0.86 | ACHE (0.49) | LMNAMAPTHTTALDH1A1HPGD | |
| SCHEMBL17089994 | 0.86 | ACHE (0.49) | LMNAMAPTHTTALDH1A1HPGD | |
| SCHEMBL13565086 | 0.84 | BRD4 (0.40) | TSHRMEN1KMT2ABRD4LMNA | |
| SCHEMBL13565482 | 0.83 | HDAC4 (0.41) | MEN1KMT2ABRD4LMNAMAPT | |
| SCHEMBL17090309 | 0.83 | HDAC4 (0.41) | MEN1KMT2ABRD4LMNAMAPT | |
| SCHEMBL13565025 | 0.83 | BRD4 (0.39) | TSHRMEN1KMT2ABRD4LMNA | |
| SCHEMBL13565488 | 0.81 | CNR2 (0.40) | CNR2 | |
| SCHEMBL17089958 | 0.81 | CNR2 (0.40) | CNR2 | |
| SCHEMBL13564856 | 0.81 | ACHE (0.42) | MEN1KMT2ALMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |