Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 16/20 | 0.40 |
| ▸ | CNR1 | P21554 | 8/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565488 | 1.00 | CNR2 (0.40) | CNR2CNR1WDR5NPY5R | |
| SCHEMBL13565719 | 0.86 | CNR2 (0.37) | CNR2CNR1WDR5NPY5R | |
| SCHEMBL13565623 | 0.84 | NPC1 (0.42) | CNR2 | |
| SCHEMBL17089960 | 0.84 | NPC1 (0.42) | CNR2 | |
| SCHEMBL10113277 | 0.83 | NPY5R (0.47) | CNR2CNR1NPY5R | |
| SCHEMBL13203812 | 0.83 | NPY5R (0.47) | CNR2CNR1NPY5R | |
| SCHEMBL17089955 | 0.82 | CNR2 (0.37) | CNR2CNR1NPY5R | |
| SCHEMBL17090307 | 0.82 | THRB (0.42) | CNR2CNR1 | |
| SCHEMBL13564763 | 0.82 | CNR2 (0.37) | CNR2CNR1NPY5R | |
| SCHEMBL13565621 | 0.82 | THRB (0.42) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |