Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 2/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13564763 | 1.00 | CNR2 (0.37) | CNR2MEN1KMT2APOLBNPY5R | |
| SCHEMBL11936194 | 0.87 | KCNH2 (0.39) | CNR2MEN1KMT2APOLBNPY5R | |
| SCHEMBL13565623 | 0.86 | NPC1 (0.42) | CNR2POLBLMNA | |
| SCHEMBL17089960 | 0.86 | NPC1 (0.42) | CNR2POLBLMNA | |
| SCHEMBL11936224 | 0.86 | NPY5R (0.42) | CNR2NPY5RCRHR1MCHR1CNR1 | |
| SCHEMBL13565593 | 0.86 | MEN1 (0.36) | MEN1KMT2APOLBMETMERTK | |
| SCHEMBL17090349 | 0.84 | MEN1 (0.35) | CNR2MEN1KMT2APOLBMET | |
| SCHEMBL17089963 | 0.83 | KMT2A (0.40) | KMT2ANPY5RMCHR1 | |
| SCHEMBL13564764 | 0.83 | KMT2A (0.40) | KMT2ANPY5RMCHR1 | |
| SCHEMBL13565488 | 0.82 | CNR2 (0.40) | CNR2NPY5RCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |