Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | MERTK | Q12866 | 3/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565593 | 0.92 | MEN1 (0.36) | MEN1POLBKMT2AMETMERTK | |
| SCHEMBL13565599 | 0.87 | NPC1 (0.41) | POLBCNR2NPC1RAB9A | |
| SCHEMBL17089955 | 0.84 | CNR2 (0.37) | MEN1POLBKMT2AMETMERTK | |
| SCHEMBL13564763 | 0.84 | CNR2 (0.37) | MEN1POLBKMT2AMETMERTK | |
| SCHEMBL10114215 | 0.83 | L3MBTL1 (0.46) | MEN1POLBKMT2AMERTKTYRO3 | |
| SCHEMBL13565055 | 0.78 | NPC1 (0.42) | POLBCNR2NPC1RAB9A | |
| SCHEMBL13438726 | 0.78 | MERTK (0.47) | MEN1POLBKMT2AMERTKAXL | |
| SCHEMBL11934855 | 0.78 | MERTK (0.47) | MEN1POLBKMT2AMERTKAXL | |
| SCHEMBL13565523 | 0.77 | LMNA (0.38) | MEN1KMT2ACRHR1NPC1RAB9A | |
| SCHEMBL13565754 | 0.76 | ACHE (0.39) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |