Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.36 |
| ▸ | GRN | P28799 | 2/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13564764 | 1.00 | KMT2A (0.40) | KMT2AUCHL1USP30RAB9ANPC1 | |
| SCHEMBL11936194 | 0.86 | KCNH2 (0.39) | KMT2AALDH1A1MAPTNPY5R | |
| SCHEMBL17089944 | 0.86 | ALDH1A1 (0.42) | ALDH1A1MAPTNPY5RGFER | |
| SCHEMBL13565600 | 0.86 | ALDH1A1 (0.42) | ALDH1A1MAPTNPY5RGFER | |
| SCHEMBL13565696 | 0.86 | KMT2A (0.40) | KMT2AUCHL1USP30RAB9ANPC1 | |
| SCHEMBL13565478 | 0.83 | CRHR1 (0.40) | KMT2ARAB9ANPC1PKMALDH1A1 | |
| SCHEMBL17090319 | 0.83 | CRHR1 (0.40) | KMT2ARAB9ANPC1PKMALDH1A1 | |
| SCHEMBL11936224 | 0.83 | NPY5R (0.42) | HPGDSNPY5RMCHR1 | |
| SCHEMBL13564763 | 0.83 | CNR2 (0.37) | KMT2ANPY5RMCHR1 | |
| SCHEMBL17089955 | 0.83 | CNR2 (0.37) | KMT2ANPY5RMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |