Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 5/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565656 | 0.86 | MAPT (0.49) | MAPTCARM1PRMT6P2RY1MAPK8 | |
| SCHEMBL10113797 | 0.86 | MAPT (0.55) | MAPTCARM1PRMT6P2RY1 | |
| SCHEMBL11934973 | 0.83 | MAPT (0.54) | MAPTCARM1PRMT6P2RY1HTR1A | |
| SCHEMBL13565433 | 0.80 | NPY5R (0.43) | P2RY1NPY5R | |
| SCHEMBL13565169 | 0.78 | GRIA1 (0.51) | NPY5R | |
| SCHEMBL13565874 | 0.77 | MAPT (0.46) | MAPTCARM1PRMT6P2RY1HTR1A | |
| SCHEMBL11935733 | 0.73 | GRIA1 (0.54) | NPY5R | |
| SCHEMBL10113525 | 0.73 | MAPT (0.55) | MAPTCARM1PRMT6P2RY1 | |
| SCHEMBL13113420 | 0.72 | MAPT (0.64) | MAPTCARM1PRMT6P2RY1HTR1A | |
| SCHEMBL13565855 | 0.71 | HTR1A (0.56) | NPY5RHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |