Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13564861 | 1.00 | POLB (0.44) | POLBEPHX1MMP8HTR2AHRH1 | |
| SCHEMBL13565419 | 0.92 | MEN1 (0.46) | POLBEPHX1MMP8HTR2AHRH1 | |
| SCHEMBL13565579 | 0.85 | SCN8A (0.38) | KMT2A | |
| SCHEMBL13565448 | 0.84 | SMYD3 (0.38) | POLBMAPTALDH1A1 | |
| SCHEMBL13564828 | 0.84 | HTR2A (0.43) | EPHX1HTR2AHRH1SIGMAR1MEN1 | |
| SCHEMBL13565454 | 0.84 | LMNA (0.38) | POLBMMP8MEN1KMT2AMAPT | |
| SCHEMBL13565548 | 0.83 | CNR2 (0.38) | KMT2A | |
| SCHEMBL10113305 | 0.83 | CYP2C19 (0.51) | POLBEPHX1MEN1KMT2AMAPT | |
| SCHEMBL13203839 | 0.83 | CYP2C19 (0.51) | POLBEPHX1MEN1KMT2AMAPT | |
| SCHEMBL13565711 | 0.82 | MAPT (0.43) | POLBMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |