Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ACHE | P22303 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565122 | 0.85 | MEN1 (0.43) | ALDH1A1KDM4EACHEMEN1KMT2A | |
| SCHEMBL13565810 | 0.85 | MEN1 (0.43) | ALDH1A1KDM4EACHEMEN1KMT2A | |
| SCHEMBL13566017 | 0.85 | ALDH1A1 (0.41) | ALDH1A1KDM4EACHEMEN1KMT2A | |
| SCHEMBL17090534 | 0.85 | ALDH1A1 (0.41) | ALDH1A1KDM4EACHEMEN1KMT2A | |
| SCHEMBL13565587 | 0.83 | GRIA2 (0.35) | — | |
| SCHEMBL17090022 | 0.83 | GRIA2 (0.35) | — | |
| SCHEMBL13565461 | 0.82 | MAOB (0.43) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL17090021 | 0.82 | MAOB (0.43) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL12882889 | 0.81 | ALDH1A1 (0.54) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11941123 | 0.81 | CA12 (0.50) | ALDH1A1KDM4ESMN1; SMN2PKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |