Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 7/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565587 | 1.00 | GRIA2 (0.35) | GRIA2NPY5RMET | |
| SCHEMBL17090116 | 0.83 | ALDH1A1 (0.45) | — | |
| SCHEMBL13439121 | 0.82 | DRD2 (0.31) | MET | |
| SCHEMBL10114793 | 0.82 | MEN1 (0.39) | GRIA2 | |
| SCHEMBL14424768 | 0.82 | MEN1 (0.39) | GRIA2 | |
| SCHEMBL13565472 | 0.78 | GRIA2 (0.35) | GRIA2NPY5R | |
| SCHEMBL11935351 | 0.76 | CA12 (0.50) | — | |
| SCHEMBL13566008 | 0.76 | NPY5R (0.33) | GRIA2NPY5R | |
| SCHEMBL11941123 | 0.76 | CA12 (0.50) | — | |
| SCHEMBL17090379 | 0.76 | NPY5R (0.33) | GRIA2NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |