Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565748 | 1.00 | BCHE (0.53) | BCHEMAPK1MAPTNPY5RMTNR1A | |
| SCHEMBL13565880 | 0.86 | NPY5R (0.62) | BCHEMAPK1MAPTNPY5RMTNR1A | |
| SCHEMBL10113302 | 0.85 | MTNR1A (0.68) | BCHEMAPTMTNR1AMEN1KMT2A | |
| SCHEMBL13203825 | 0.85 | MTNR1A (0.68) | BCHEMAPTMTNR1AMEN1KMT2A | |
| SCHEMBL1968351 | 0.83 | BCHE (0.67) | BCHEMAPK1MAPTMTNR1AMEN1 | |
| SCHEMBL13565419 | 0.79 | MEN1 (0.46) | MAPTMEN1KMT2ALMNATSHR | |
| SCHEMBL13564832 | 0.79 | SLC2A1 (0.39) | BCHENPY5RHTR2AHTR1A | |
| SCHEMBL20689740 | 0.79 | BCHE (0.64) | BCHEMAPK1MAPTMTNR1AMEN1 | |
| SCHEMBL22221910 | 0.79 | BCHE (0.76) | BCHEMAPK1MAPTMTNR1AMEN1 | |
| SCHEMBL22222026 | 0.79 | BCHE (0.72) | BCHEMAPK1MAPTMTNR1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |