Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.46 |
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 9/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13439076 | 0.97 | ALDH1A1 (0.45) | ALDH1A1RAB9AKDM4EHPGDMEN1 | |
| SCHEMBL17090239 | 0.86 | ALDH1A1 (0.47) | ALDH1A1RAB9AKDM4EHPGDMEN1 | |
| SCHEMBL13565336 | 0.84 | POLB (0.39) | ALDH1A1RAB9AKDM4EHPGDMEN1 | |
| SCHEMBL10114639 | 0.83 | ALDH1A1 (0.55) | ALDH1A1RAB9AKDM4EHPGDMEN1 | |
| SCHEMBL13439077 | 0.83 | ALDH1A1 (0.47) | ALDH1A1RAB9AKDM4EHPGDMEN1 | |
| SCHEMBL13565192 | 0.83 | CNR2 (0.34) | ALDH1A1RAB9AKDM4EHPGDMEN1 | |
| SCHEMBL13565320 | 0.82 | ALDH1A1 (0.40) | ALDH1A1RAB9AKDM4EHPGDMEN1 | |
| SCHEMBL13564882 | 0.81 | CNR2 (0.44) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL13565967 | 0.78 | ALDH1A1 (0.38) | ALDH1A1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL11935360 | 0.78 | ALDH1A1 (0.53) | ALDH1A1RAB9AKDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |