Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 2/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565938 | 1.00 | L3MBTL1 (0.35) | L3MBTL1CRHBPCRHR2ADRB3POLB | |
| SCHEMBL13566037 | 0.88 | KDM4E (0.38) | L3MBTL1CRHBPCRHR2ADRB3HSD11B1 | |
| SCHEMBL17090286 | 0.88 | KDM4E (0.38) | L3MBTL1CRHBPCRHR2ADRB3HSD11B1 | |
| SCHEMBL17090292 | 0.87 | L3MBTL1 (0.33) | L3MBTL1CRHBPCRHR2POLB | |
| SCHEMBL13565966 | 0.87 | L3MBTL1 (0.35) | L3MBTL1CRHBPCRHR2ADRB3POLB | |
| SCHEMBL17090553 | 0.87 | L3MBTL1 (0.35) | L3MBTL1CRHBPCRHR2ADRB3POLB | |
| SCHEMBL13565803 | 0.86 | L3MBTL1 (0.30) | L3MBTL1CRHBPCRHR2 | |
| SCHEMBL17090245 | 0.86 | L3MBTL1 (0.30) | L3MBTL1CRHBPCRHR2 | |
| SCHEMBL10116329 | 0.83 | CRHBP (0.40) | CRHBPCRHR2ALDH1A1 | |
| SCHEMBL10134529 | 0.83 | CRHBP (0.40) | CRHBPCRHR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |