Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11936045 | 0.85 | PRMT6 (0.40) | PRMT6MAPTRXFP1CLK4ALDH1A1 | |
| SCHEMBL17090484 | 0.81 | EDNRA (0.35) | — | |
| SCHEMBL11936142 | 0.80 | PRMT6 (0.45) | PRMT6MAPTRXFP1CLK4ALDH1A1 | |
| SCHEMBL13565228 | 0.78 | CYP3A4 (0.40) | PRMT6MAPTRXFP1CLK4ALDH1A1 | |
| SCHEMBL10116746 | 0.78 | HDAC2 (0.46) | MAPTALDH1A1TP53MEN1KMT2A | |
| SCHEMBL11936007 | 0.77 | TAAR1 (0.50) | PRMT6MAPTRXFP1CLK4ALDH1A1 | |
| SCHEMBL13113870 | 0.75 | CYP3A4 (0.45) | MAPTALDH1A1PTGES2TP53HCRTR2 | |
| SCHEMBL13565333 | 0.74 | GRIA4 (0.35) | PRMT6MAPTCLK4ALDH1A1CRHBP | |
| SCHEMBL11936140 | 0.74 | PRMT6 (0.44) | PRMT6MAPTTP53CYP3A4CYP1A2 | |
| SCHEMBL13564938 | 0.73 | GRIA2 (0.38) | HCRTR2CYP1A2GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |