Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 13/20 | 0.35 |
| ▸ | EDNRB | P24530 | 12/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.35 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565946 | 0.91 | PPARA (0.37) | EDNRAEDNRBP2RX7 | |
| SCHEMBL11936053 | 0.86 | EDNRA (0.37) | EDNRAEDNRBP2RX7TTK | |
| SCHEMBL17090258 | 0.81 | PRMT6 (0.40) | — | |
| SCHEMBL11936017 | 0.81 | SMN1; SMN2 (0.39) | P2RX7TTK | |
| SCHEMBL13565042 | 0.79 | EDNRA (0.37) | EDNRAEDNRBP2RX7TTK | |
| SCHEMBL10116739 | 0.79 | MAPT (0.43) | EDNRA | |
| SCHEMBL13564985 | 0.78 | NPY5R (0.41) | EDNRAEDNRBTTK | |
| SCHEMBL11936042 | 0.78 | PDPK1 (0.38) | P2RX7TTK | |
| SCHEMBL13565252 | 0.76 | LTA4H (0.41) | EDNRAEDNRB | |
| SCHEMBL13565222 | 0.75 | GRIA4 (0.34) | EDNRAEDNRBP2RX7TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |