Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13566005 | 1.00 | POLB (0.39) | POLBCNR2KDM4EPGAM1MAPT | |
| SCHEMBL13565191 | 1.00 | POLB (0.39) | POLBCNR2KDM4EPGAM1MAPT | |
| SCHEMBL17090265 | 1.00 | POLB (0.39) | POLBCNR2KDM4EPGAM1MAPT | |
| SCHEMBL11940986 | 0.87 | MAPT (0.44) | CNR2MAPTBRD4 | |
| SCHEMBL11934925 | 0.87 | MAPT (0.44) | CNR2MAPTBRD4 | |
| SCHEMBL17090267 | 0.87 | MAPT (0.44) | CNR2MAPTBRD4 | |
| SCHEMBL13564924 | 0.84 | CNR2 (0.35) | POLBCNR2KDM4EMAPTALDH1A1 | |
| SCHEMBL13565311 | 0.84 | GRIA1 (0.44) | POLBCNR2PGAM1MAPTALDH1A1 | |
| SCHEMBL17090210 | 0.84 | GRIA1 (0.44) | POLBCNR2PGAM1MAPTALDH1A1 | |
| SCHEMBL17090209 | 0.84 | GRIA1 (0.44) | POLBCNR2PGAM1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |