Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 6/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11934925 | 1.00 | MAPT (0.44) | MAPTNPY5RBRD4LRRK2CNR2 | |
| SCHEMBL11940986 | 1.00 | MAPT (0.44) | MAPTNPY5RBRD4LRRK2CNR2 | |
| SCHEMBL13565191 | 0.87 | POLB (0.39) | MAPTBRD4CNR2 | |
| SCHEMBL17090265 | 0.87 | POLB (0.39) | MAPTBRD4CNR2 | |
| SCHEMBL17090264 | 0.87 | POLB (0.39) | MAPTBRD4CNR2 | |
| SCHEMBL13566005 | 0.87 | POLB (0.39) | MAPTBRD4CNR2 | |
| SCHEMBL17090394 | 0.87 | GHSR (0.39) | NPY5RBRD4 | |
| SCHEMBL13565733 | 0.87 | GHSR (0.39) | NPY5RBRD4 | |
| SCHEMBL17090204 | 0.85 | BRD4 (0.38) | MAPTNPY5RBRD4 | |
| SCHEMBL11935550 | 0.85 | BRD4 (0.41) | MAPTNPY5RBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |