Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | DDIT3 | P35638 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565245 | 1.00 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1GAATSHRLMNA | |
| SCHEMBL17090270 | 0.88 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1GAATSHRLMNA | |
| SCHEMBL13565248 | 0.88 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1GAATSHRLMNA | |
| SCHEMBL17090428 | 0.85 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1GAATSHRLMNA | |
| SCHEMBL14418520 | 0.85 | ALDH1A1 (0.61) | SMN1; SMN2ALDH1A1GAALMNAHTT | |
| SCHEMBL10134474 | 0.85 | ALDH1A1 (0.61) | SMN1; SMN2ALDH1A1GAALMNAHTT | |
| SCHEMBL10115022 | 0.85 | ALDH1A1 (0.61) | SMN1; SMN2ALDH1A1GAALMNAHTT | |
| SCHEMBL17090267 | 0.84 | MAPT (0.44) | MAPTNPY5R | |
| SCHEMBL11940986 | 0.84 | MAPT (0.44) | MAPTNPY5R | |
| SCHEMBL11934925 | 0.84 | MAPT (0.44) | MAPTNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |