Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565139 | 1.00 | TRPA1 (0.35) | TRPA1ALDH1A1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL13105787 | 0.88 | GRIA1 (0.39) | TRPA1ALDH1A1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL11935751 | 0.88 | GRIA1 (0.39) | TRPA1ALDH1A1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL10115046 | 0.86 | CNR1 (0.43) | ALDH1A1MAPTL3MBTL1SMN1; SMN2GAA | |
| SCHEMBL10133453 | 0.86 | CNR1 (0.43) | ALDH1A1MAPTL3MBTL1SMN1; SMN2GAA | |
| SCHEMBL11934898 | 0.83 | L3MBTL1 (0.45) | ALDH1A1MAPTL3MBTL1SMN1; SMN2GAA | |
| SCHEMBL13105730 | 0.82 | SYK (0.38) | ALDH1A1MAPTL3MBTL1SMN1; SMN2GAA | |
| SCHEMBL11935577 | 0.82 | SYK (0.38) | ALDH1A1MAPTL3MBTL1SMN1; SMN2GAA | |
| SCHEMBL11935907 | 0.80 | MAPT (0.47) | ALDH1A1MAPTL3MBTL1SMN1; SMN2GAA | |
| SCHEMBL11940097 | 0.80 | MAPT (0.47) | ALDH1A1MAPTL3MBTL1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |