Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 3/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13204598 | 0.84 | ALDH1A1 (0.38) | GRIA1HTR1A | |
| SCHEMBL13565348 | 0.83 | GRIA1 (0.43) | GRIA1NPY5RHTR1A | |
| SCHEMBL13565326 | 0.81 | GRIA1 (0.43) | GRIA1NPY5RHTR1A | |
| SCHEMBL13565632 | 0.72 | GRIA1 (0.41) | GRIA1NPY5RHTR1A | |
| SCHEMBL11935809 | 0.72 | GRIA1 (0.46) | GRIA1NPY5RHTR1A | |
| SCHEMBL13565328 | 0.71 | GRIA1 (0.59) | GRIA1NPY5RHTR1A | |
| SCHEMBL10115241 | 0.70 | ALDH1A1 (0.38) | — | |
| SCHEMBL11935306 | 0.69 | NPY5R (0.54) | GRIA1NPY5R | |
| SCHEMBL13565345 | 0.69 | CNR2 (0.34) | — | |
| SCHEMBL13565796 | 0.69 | GRIA1 (0.51) | GRIA1NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |