Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 9/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 8/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 4/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11935080 | 0.89 | HTR1A (0.50) | GRIA1MEN1KMT2AHTR1ANPY5R | |
| SCHEMBL17090462 | 0.86 | GRIA1 (0.44) | HTR7GRIA1HTR1ANPY5RCA12 | |
| SCHEMBL11935774 | 0.86 | NPSR1 (0.45) | HTR7GRIA1HTR1ANPY5R | |
| SCHEMBL10113893 | 0.85 | MEN1 (0.68) | MEN1KMT2AHTR1APARP1PARP10 | |
| SCHEMBL11935609 | 0.83 | HTR7 (0.47) | HTR7MEN1KMT2APARP1PARP10 | |
| SCHEMBL13565857 | 0.82 | GRIA1 (0.51) | HTR7GRIA1MEN1KMT2AHTR1A | |
| SCHEMBL11935051 | 0.82 | GRIA1 (0.51) | GRIA1HTR1ANPY5R | |
| SCHEMBL11935049 | 0.81 | HTR1A (0.61) | GRIA1MEN1KMT2AHTR1A | |
| SCHEMBL11935749 | 0.81 | GRIA1 (0.53) | GRIA1HTR1ANPY5R | |
| SCHEMBL13565339 | 0.81 | GRIA1 (0.53) | GRIA1MEN1KMT2AHTR1ANPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |