Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17090453 | 0.85 | GRIA1 (0.46) | GRIA1ALDH1A1KMT2APKMNPY5R | |
| SCHEMBL11935686 | 0.84 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AMAPTPKM | |
| SCHEMBL11935672 | 0.83 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AMAPTPKM | |
| SCHEMBL13565890 | 0.82 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL17090457 | 0.82 | ALDH1A1 (0.51) | GRIA1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11935729 | 0.81 | GRIA1 (0.59) | GRIA1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL13564968 | 0.81 | GRIA1 (0.59) | GRIA1ALDH1A1MEN1KMT2APKM | |
| SCHEMBL10115436 | 0.81 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2APKMSMN1; SMN2 | |
| SCHEMBL13565298 | 0.80 | GRIA1 (0.58) | GRIA1ALDH1A1MEN1KMT2ANPY5R | |
| SCHEMBL13564814 | 0.80 | GRIA1 (0.58) | GRIA1ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |